Solving Controlled Release Drug Delivery Challenges Using Extrusion-Spheronization

Solving Drug Delivery Challenges Using Extrusion-SpheronizationSynchronizing and controlling API delivery, Extrusion-Spheronization (E-S) offers pharmaceutical drug developers a robust technique to develop and manufacture today’s most complex oral sold dose therapeutics.

Manufacturing oral solid dose API's into spheres via Extrusion-Spheronization is not new. What is new is that in the right hands, with the right capabilities, this well-understood process stands ready to help lead the development and manufacturing of both today and tomorrow’s complex solid dose therapeutics.


In this whitepaper, you will explore: 

  • How delivering therapeutic compounds and molecules via spheronized forms will support your most challenging drug product manufacturing goals.
  • Insights into the drivers behind using extrusion-spheronization to support patient friendly oral solid dose drug strategies.
  • An understanding of how extrusion-spheronization can improve quality, safety, therapeutic efficacy and dose compliance across a diverse range of therapeutic areas.
  • Applications of extrusion-spheronization technology for both modified release capsules and multi-unit pellet systems (MUPS).
  • A step-by-step guide the E-S manufacturing process.